Mims Medical Microbiology Electronic 6th Edition by Richard Goering ISBN 070207201X 9780702072017

Mims Medical Microbiology Electronic 6th Edition by Richard Goering – Ebook PDF Instant Download/Delivery. 070207201X, 9780702072017
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ISBN 10: 070207201X 
ISBN 13: 9780702072017
Author: Richard Goering

Learn all the microbiology and basic immunology concepts you need to know for your courses and exams. Now fully revised and updated, Mims’ clinically relevant, systems-based approach and abundant colour illustrations make this complex subject easy to understand and remember.

• Learn about infections in the context of major body systems and understand why these are environments in which microbes can establish themselves, flourish, and give rise to pathologic changes. This systems-based approach to microbiology employs integrated and case-based teaching that places the ‘bug parade’ into a clinical context.
• Effectively review for problem-based courses with the help of chapter introductions and ‘Lessons in Microbiology’ text boxes that highlight the clinical relevance of the material, offer easy access to key concepts, and provide valuable review tools.
• Approach microbiology by body system or by pathogen through the accompanying electronic ‘Pathogen Parade’ – a quickly searchable, cross-referenced glossary of viruses, bacteria and fungi
• A new electronic ‘Vaccine Parade’ offers quick-reference coverage of the most commonly used vaccines in current clinical practice
• Deepen your understanding of epidemiology and the important role it plays in providing evidence-based identification of key risk factors for disease and targets for preventative medicine.
• Grasp and retain vital concepts easily, with a user-friendly colour coded format, succinct text, key concept boxes, and dynamic illustrations.
• New and enhanced information reflects the growing importance of the human microbiota and latest molecular approaches
• Access the complete contents on the go via the accompanying interactive eBook, with a range of bonus materials to enhance learning and retention – includes self-assessment materials and clinical cases to check your understanding and aid exam preparation.

Mims Medical Microbiology Electronic 6th Table of contents:

Section 1 The Adversaries – Pathogens
Introduction
1 Pathogens as parasites
The Varieties of Pathogens
Living Inside or Outside Cells
Systems of Classification
2 The bacteria
Structure
Nutrition
Growth and Division
Gene Expression
Survival Under Adverse Conditions
Mobile Genetic Elements
Mutation and Gene Transfer
The Genomics of Medically Important Bacteria
3 The viruses
Major Groups of Viruses
Infection of Host Cells
Replication
Outcome of Viral Infection
4 The fungi
Major Groups of Disease-Causing Fungi
5 The protozoa
6 The helminths
Life Cycles
Helminths and Disease
7 The arthropods
8 Prions
‘Rogue Protein’ Pathogenesis
Development, Transmission and Diagnosis of Prion Diseases
Prevention and Treatment of Prion Diseases
9 The host–parasite relationship
The Microbiota and Microbiome
Symbiotic Associations
The Characteristics of Parasitism
The Evolution of Parasitism
Section 2 The Adversaries – Host Defences
Introduction
10 The innate defences of the body
Defences Against Entry Into the Body
Defences Once the Microorganism Penetrates the Body
11 Adaptive immune responses bring specificity
Lymphoid Tissues Primary and Secondary
Secondary Lymphoid Organs
Subsets of T Cells
Antibody Structure and Function
Recirculation of T and B Cells
12 Cooperation leads to effective immune responses
Cooperation Means Greater Efficiency
Opsonization by Antibody Enhances Phagocytosis and Leads to Complement Activation
Beneficial Inflammatory Reactions Can Also Be Enhanced by Antibodies
Activation of T Cells Involves Antigen-Presenting Cells and Additional Co-Stimulatory Signals
Clonal Expansion
Antibody Production Involves a Series of Steps Within the Germinal Centre
Cytokines Play an Important Part in These Cell–Cell Interactions
Immunological Memory Enables a Second Infection With the Same Microbe to Be Dealt With More Effectively
Armies Must Be Kept Under Control
Section 3 The Conflicts
Introduction
13 Background to the infectious diseases
Host–Parasite Relationships
Causes of Infectious Diseases
The Biological Response Gradient
14 Entry, exit and transmission
Sites of Entry
Exit and Transmission
Types of Transmission Between Humans
Transmission From Animals
15 Immune defences in action
Complement
Acute Phase Proteins and Pattern Recognition Receptors
Fever
Natural Killer Cells
Phagocytosis
Cytokines
Antibody-Mediated Immunity
Cell-Mediated Immunity
Recovery From Infection
16 Spread and replication
Features of Surface and Systemic Infections
Mechanisms of Spread Through the Body
Genetic Determinants of Spread and Replication
Other Factors Affecting Spread and Replication
17 Parasite survival strategies and persistent infections
Parasite Survival Strategies
Concealment of Antigens
Antigenic Variation
Immunosuppression
Persistent Infections
18 Pathological consequences of infection
Pathology Caused Directly by Microorganisms
Diarrhoea
Pathological Activation of Natural Immune Mechanisms
Pathological Consequences of the Immune Response
Skin Rashes
Viruses and Cancer
Section 4 Clinical Manifestation and Diagnosis of Infections by Body System
Introduction
The Clinical Manifestations of Infection
19 Upper respiratory tract infections
Rhinitis
Pharyngitis and Tonsillitis
Parotitis
Otitis and Sinusitis
Acute Epiglottitis
Oral Cavity Infections
20 Lower respiratory tract infections
Laryngitis and Tracheitis
Diphtheria
Whooping Cough
Acute Bronchitis
Acute Exacerbations of Chronic Bronchitis
Bronchiolitis
Respiratory Syncytial Virus (RSV) Infection
Hantavirus Pulmonary Syndrome (HPS)
Pneumonia
Bacterial Pneumonia
Viral Pneumonia
Parainfluenza Virus Infection
Adenovirus Infection
Human Metapneumovirus Infection
Human Bocavirus Infection
Influenza Virus Infection
Severe Acute Respiratory Syndrome and Middle East Respiratory Syndrome Coronavirus Infections
Measles Virus Infection
Cytomegalovirus Infection
Tuberculosis
Cystic Fibrosis
Lung Abscess
Fungal Infections
Protozoal Infections
21 Urinary tract infections
Acquisition and Aetiology
Pathogenesis
Clinical Features and Complications
Laboratory Diagnosis
Treatment
Prevention
22 Sexually transmitted infections
Stis and Sexual Behaviour
Syphilis
Gonorrhoea
Chlamydial Infection
Other Causes of Inguinal Lymphadenopathy
Mycoplasmas and Non-Gonococcal Urethritis
Other Causes of Vaginitis and Urethritis
Genital Herpes
Human Papillomavirus Infection
Human Immunodeficiency Virus
Opportunist Stis
Arthropod Infestations
23 Gastrointestinal tract infections
Diarrhoeal Diseases Caused by Bacterial or Viral Infection
Food Poisoning – Bacterial Toxin-Associated Diarrhoea
Viral Causes of Diarrhoea
Helicobacter Pylori and Gastric Ulcer Disease
Parasites and the Gastrointestinal Tract
Systemic Infection Initiated in the Gastrointestinal Tract
24 Obstetric and perinatal infections
Infections Occurring in Pregnancy
Congenital Infections
Infections Occurring Around the Time of Birth
25 Central nervous system infections
Invasion of the Central Nervous System
The Body’s Response to Invasion
Meningitis
Encephalitis
Neurological Diseases of Possible Viral Aetiology
Spongiform Encephalopathies Caused by Scrapie-Type Agents
CNS Disease Caused by Parasites
Brain Abscesses
Tetanus and Botulism
26 Infections of the eye
Conjunctivitis
Infection of the Deeper Layers of the Eye
27 Infections of the skin, soft tissue, muscle and associated systems
Bacterial Infections of Skin, Soft Tissue and Muscle
Mycobacterial Diseases of the Skin
Fungal Infections of the Skin
Parasitic Infections of the Skin
Mucocutaneous Manifestations of Viral Infections
Smallpox Virus Infection
Measles Virus Infection
Rubella Virus Infection
Other Maculopapular Rashes Associated With Travel-Related Infections
Other Infections Producing Skin Lesions
Kawasaki Syndrome
Viral Infections of Muscle
Parasitic Infections of Muscle
Joint and Bone Infections
Infections of the Haemopoietic System
28 Vector-borne infections
Arbovirus Infections
Infections Caused by Rickettsiae
Borrelia Infections
Protozoal Infections
Helminth Infections
29 Multisystem zoonoses
Arenavirus Infections
Haemorrhagic Fever With Renal Syndrome (HFRS)
Ebola and Marburg Haemorrhagic Fevers
Crimean–Congo Haemorrhagic Fever, a Tick-Borne Virus
Q Fever
Anthrax
Plague
Yersinia Enterocolitica Infection
Tularaemia
Pasteurella Multocida Infection
Leptospirosis
Rat-Bite Fever
Brucellosis
Helminth Infections
30 Fever of unknown origin
Definitions of Fever of Unknown Origin
Causes of FUO
Investigation of Classic FUO
Treatment of FUO
FUO in Specific Patient Groups
Infective Endocarditis
31 Infections in the compromised host
The Compromised Host
Infections of the Host With Deficient Innate Immunity Due to Physical Factors
Infections Associated With Secondary Adaptive Immunodeficiency
Other Important Opportunist Pathogens
Section 5 Diagnosis and Control
Introduction
32 Diagnosis of infection and assessment of host defence mechanisms
Aims of the Clinical Microbiology Laboratory
Specimen Processing
Cultivation (Culture) of Microorganisms
Identification of Microorganisms Grown in Culture
Non-Cultural Techniques for the Laboratory Diagnosis of Infection
Antibody Detection Methods for the Diagnosis of Infection
Assessment of Host Defence Systems
Putting It All Together: Detection, Diagnosis and Epidemiology
33 Epidemiology and control of infectious diseases
Outcome Measurements
Types of Epidemiological Studies
Transmission of Infectious Disease
Vaccine Efficacy
34 Attacking the enemy
Selective Toxicity
Discovery and Design of Antimicrobial Agents
Classification of Antibacterial Agents
Resistance to Antibacterial Agents
Classes of Antibacterial Agents
Inhibitors of Cell Wall Synthesis
Inhibitors of Protein Synthesis
Inhibitors of Nucleic Acid Synthesis
Antimetabolites Affecting Nucleic Acid Synthesis
Other Agents That Affect DNA
Inhibitors of Cytoplasmic Membrane Function
Urinary Tract Antiseptics
Antituberculosis Agents
Antibacterial Agents in Practice
Antibiotic Assays
Antiviral Therapy
Antifungal Agents
Antiparasitic Agents
Control by Chemotherapy Versus Vaccination
Control Versus Eradication
Use and Misuse of Antimicrobial Agents
35 Protecting the host
Vaccination – a Four Hundred Year History
Aims of Vaccination
Vaccines Can Be of Different Types
36 Active, passive and adoptive immunotherapy
Adoptive Immunotherapy
Passive Immunotherapy
Non-Specific Cellular Immunostimulation
Correction of Host Immunodeficiency
Probiotics
37 Infection control
Common Hospital Infections
Important Causes of Hospital Infection
Sources and Routes of Spread of Hospital Infection
Host Factors and Hospital Infection
Consequences of Hospital Infection
Prevention of Hospital Infection
Investigating Healthcare-Associated Infection
Sterilization and Disinfection
Bibliography – list of useful websites

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