Dento Oro Craniofacial Anomalies and Genetics 1st Edition by Agnes Bloch Zupan, Heddie Sedano, Crispian Scully ISBN 0124160387 9780124160385

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Product details:

ISBN 10: 0124160387 
ISBN 13: 9780124160385
Author: Agnes Bloch Zupan, Heddie Sedano, Crispian Scully

Dental defects may be the physical expression of genetic defects, and so they can often be seen in a variety of syndromes associated with malformations of organs. However, dental defects are often not recognized, identified, nor characterised despite representing a possible diagnostic sign for an undiagnosed condition. This book addresses this gap by providing an understanding of dental genetics and its developmental biology counterpart. With approximately seventy well-illustrated examples, the authors present the clinical oro-facial manifestations accompanying various syndromes, providing the necessary knowledge for diagnostic purposes, as well as giving insight into recent development for each specific condition. The clarity and format of this book make it an ideal support guide both in the clinic and while conducting research.

• Comprehensive examination of dento/oro/craniofacial anomalies
• Well-illustrated examples
• Presented in a compact, easy to use format

Dento/Oro/Craniofacial Anomalies and Genetics 1st Table of contents:

1. Odontogenesis, Anomalies and Genetics
1.1 Odontogenesis
1.2 Dental Anomalies
1.3 Syndromes and Dental Anomalies
2. Missing Teeth (Hypodontia and Oligodontia)
2.1 Transcription Factors
2.2 WNT Signalling Pathway
2.3 TNF/NF-Kappa B Signalling Pathway
2.4 TGFbeta Superfamily
2.5 SHH Signalling Pathway
2.6 Fibroblast Growth Factors (FGF) Pathway
2.7 Other Pathways
3. Supernumerary Teeth
3.1 Cleidocranial Dysplasia (CCD)
3.2 Familial Adenomatous Polyposis (FAP)
3.3 Nance-Horan Syndrome (NHS)
3.4 Tricho-Rhino-Phalangeal Syndromes
4. Abnormalities of Tooth Shape and Size
4.1 Rubinstein-Taybi Syndrome (RTS)
4.2 Otodental Syndrome
4.3 Oculo-Facio-Cardio-Dental Syndrome (OFCD)
4.4 KBG Syndrome (Herrmann-Pallister-Opitz Syndrome)
5. Anomalies in Structure of Teeth – Dentine
5.1 Dentinogenesis Imperfecta Type II and DGI-II or Hereditary Opalescent Dentine
5.2 Dentinogenesis Imperfecta Type III (DGI-III)
5.3 Dentine Dysplasia
5.4 Osteogenesis Imperfecta (OI)
6. Anomalies Structure of Teeth – Enamel
6.1 Amelogenesis Imperfecta
6.2 Syndrome with Enamel Defects
7. Anomalies of Teeth Eruption and/or Resorption
7.1 Sotos Syndrome (Cerebral Gigantism)
7.2 Hypophosphataemic Vitamin D-Resistant Rickets, Hypophosphataemia X-Linked
7.3 Osteopetrosis
7.4 Hypophosphatasia
7.5 Papillon–Lefèvre Syndrome (PLS)
7.6 Haim–Munk Syndrome (Cochin Jewish Disorder, Congenital Keratosis Palmoplantaris)
7.7 Familial Expansile Osteolysis Syndrome
8. Pathology and Dental Anomalies
8.1 Naevoid Basal Cell Carcinoma Syndrome (NBCCS; Gorlin syndrome)
8.2 Cherubism

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