Genetic Variants in Periodontal Health and Disease 1st edition by Dumitrescu ISBN 3642006795 9783642006791

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Product details:

ISBN 10:       3642006795
ISBN 13: 978-3642006791
Author:        Dumitrescu

Genetic Variants in Periodontal Health and Disease 1st Table of contents:

1. Introduction to Genetics in Periodontal Health and Disease

• Overview of genetic research in periodontology
• The role of genetic variants in health and disease
• Mechanisms linking genetics to periodontal disease susceptibility
• Objectives and scope of the book

2. Genetic Factors in Periodontal Health

• Overview of periodontal health and its genetic underpinnings
• Genetic variants associated with resistance to periodontal diseases
• Immune system genetics in periodontal health
• Host response to oral bacteria: Genetic perspectives

3. Genetic Risk Factors for Periodontal Disease

• Understanding susceptibility to periodontal disease
• Common genetic variations linked to periodontal diseases
• Interaction between genetic factors and environmental influences
• Risk assessment and personalized approaches based on genetic data

4. Genetic Polymorphisms and Inflammatory Responses

• Inflammatory pathways in periodontal disease
• Key genetic polymorphisms involved in inflammation
• The role of cytokine gene variations in periodontal disease
• Implications for disease progression and treatment responses

5. Host-Microbe Interactions in Periodontal Disease

• Genetic variations affecting the host’s immune response to microbes
• Interactions between microbial pathogens and host genetics
• Periodontal disease as a host-microbe imbalance
• Genetic variants influencing oral microbiota composition

6. Gene Expression and Epigenetics in Periodontal Disease

• The role of gene expression in periodontal health and disease
• Epigenetic mechanisms in periodontal disease progression
• DNA methylation, histone modification, and their impact on periodontal tissues
• Epigenetic influences on inflammation and tissue remodeling in periodontitis

7. Genetic Approaches to Periodontal Disease Diagnosis

• Genetic biomarkers for periodontal disease detection
• Diagnostic tools based on genetic information
• Implications for early detection and precision medicine
• Limitations and challenges in genetic-based diagnostics

8. Genetic Variants in Periodontal Regeneration and Healing

• Genetic influences on periodontal tissue regeneration
• The role of stem cells and genetic factors in healing
• Variations in genes related to tissue repair and regeneration
• Genetic contributions to the outcomes of periodontal treatments

9. Pharmacogenomics in Periodontal Therapy

• Genetic factors influencing drug response in periodontal therapy
• Genetic markers for predicting treatment outcomes
• The role of genetics in customizing periodontal treatment plans
• Pharmacogenomics and the future of personalized periodontal care

10. Ethical, Legal, and Social Implications of Genetic Research in Periodontology

• Ethical considerations in genetic testing for periodontal disease
• Privacy, consent, and genetic data sharing
• Societal implications of genetic-based periodontal care
• The future of genetics in public health and periodontology

11. Future Directions in Genetic Research for Periodontal Disease

• Emerging technologies in genetic research
• The role of next-generation sequencing in periodontal studies
• Integrating genomics with clinical practice
• Prospects for personalized prevention and treatment strategies

12. Conclusions

• Summary of genetic insights into periodontal health and disease
• Key findings and their impact on periodontal care
• Final thoughts and future research directions

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