Essential Biochemistry 4th Edition by Charlotte Pratt, Kathleen Cornely ISBN 1119444373 9781119444374
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Authors:Charlotte W. Pratt; Kathleen Cornely , Tags:Medical; Biochemistry , Author sort:Pratt, Charlotte W. & Cornely, Kathleen , Ids:9781119319337 , Languages:Languages:eng , Published:Published:Dec 2018 , Publisher:John Wiley & Sons Incorporated , Comments:Comments:No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning or otherwise, except as permitted under Sections 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923, (978) 750-8400, fax (978) 646-8600. Requests to the Publisher for permission should be addressed to the Permissions Department, John Wiley Sons, Inc., 111 River Street, Hoboken, NJ 07030-5774, (201) 748-6011, fax (201) 748-6008. Evaluation copies are provided to qualifi ed academics and professionals for review purposes only, for use in their courses during the next academic year. These copies are licensed and may not be sold or transferred to a third party. Upon completion of the review period, please return the evaluation copy to Wiley. Return instructions and a free of charge return shipping label are available at www.wiley.com/go/ returnlabel. Outside of the United States, please contact your local representative.
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ISBN 10: 1119444373
ISBN 13: 978-1119444374
Author: Charlotte W. Pratt, Kathleen Cornely
Essential Biochemistry 4th Table of contents:
Chapter 1: The Chemical Basis of Life
1.1 What Is Biochemistry?
1.2 Biological Molecules
1.3 Energy and Metabolism
1.4 The Origin and Evolution of Life
Chapter 2: Aqueous Chemistry
2.1 Water Molecules and Hydrogen Bonds
2.2 The Hydrophobic Effect
2.3 Acid–Base Chemistry
2.4 Tools and Techniques: Buffers
2.5 Clinical Connection: Acid–Base Balance in Humans
Chapter 3: From Genes to Proteins
3.1 Nucleotides
3.2 Nucleic Acid Structure
3.3 The Central Dogma
3.4 Genomics
3.5 Tools and Techniques: Manipulating DNA
Chapter 4: Protein Structure
4.1 Amino Acids, the Building Blocks of Proteins
4.2 Secondary Structure: The Conformation of the Peptide Group
4.3 Tertiary Structure and Protein Stability
4.4 Quaternary Structure
4.5 Clinical Connection: Protein Misfolding and Disease
4.6 Tools and Techniques: Analyzing Protein Structure
Chapter 5: Protein Function
5.1 Myoglobin and Hemoglobin: Oxygen-Binding Proteins
5.2 Clinical Connection: Hemoglobin Variants
5.3 Structural Proteins
5.4 Motor Proteins
Chapter 6: How Enzymes Work
6.1 What Is an Enzyme?
6.2 Chemical Catalytic Mechanisms
6.3 Unique Properties of Enzyme Catalysts
6.4 Chymotrypsin in Context
6.5 Clinical Connection: Blood Coagulation
Chapter 7: Enzyme Kinetics and Inhibition
7.1 Introduction to Enzyme Kinetics
7.2 Derivation and Meaning of the Michaelis–Menten Equation
7.3 Enzyme Inhibition
7.4 Clinical Connection: Drug Development
Chapter 8: Lipids and Membranes
8.1 Lipids
8.2 The Lipid Bilayer
8.3 Membrane Proteins
8.4 The Fluid Mosaic Model
Chapter 9: Membrane Transport
9.1 The Thermodynamics of Membrane Transport
9.2 Passive Transport
9.3 Active Transport
9.4 Membrane Fusion
Chapter 10: Signaling
10.1 General Features of Signaling Pathways
10.2 G Protein Signaling Pathways
10.3 Receptor Tyrosine Kinases
10.4 Lipid Hormone Signaling
Chapter 11: Carbohydrates
11.1 Monosaccharides
11.2 Polysaccharides
11.3 Glycoproteins
Chapter 12: Metabolism and Bioenergetics
12.1 Food and Fuel
12.2 Metabolic Pathways
12.3 Free Energy Changes in Metabolic Reactions
Chapter 13: Glucose Metabolism
13.1 Glycolysis
13.2 Gluconeogenesis
13.3 Glycogen Synthesis and Degradation
13.4 The Pentose Phosphate Pathway
13.5 Clinical Connection: Disorders of Carbohydrate Metabolism
Chapter 14: The Citric Acid Cycle
14.1 The Pyruvate Dehydrogenase Reaction
14.2 The Eight Reactions of the Citric Acid Cycle
14.3 Thermodynamics of the Citric Acid Cycle
14.4 Anabolic and Catabolic Functions of the Citric Acid Cycle
Chapter 15: Oxidative Phosphorylation
15.1 The Thermodynamics of Oxidation–Reduction Reactions
15.2 Mitochondrial Electron Transport
15.3 Chemiosmosis
15.4 ATP Synthase
Chapter 16: Photosynthesis
16.1 Chloroplasts and Solar Energy
16.2 The Light Reactions
16.3 Carbon Fixation
Chapter 17: Lipid Metabolism
17.1 Lipid Transport
17.2 Fatty Acid Oxidation
17.3 Fatty Acid Synthesis
17.4 Synthesis of Other Lipids
Chapter 18: Nitrogen Metabolism
18.1 Nitrogen Fixation and Assimilation
18.2 Amino Acid Biosynthesis
18.3 Amino Acid Catabolism
18.4 Nitrogen Disposal: The Urea Cycle
18.5 Nucleotide Metabolism
Chapter 19: Regulation of Mammalian Fuel Metabolism
19.1 Integration of Fuel Metabolism
19.2 Hormonal Control of Fuel Metabolism
19.3 Disorders of Fuel Metabolism
19.4 Clinical Connection: Cancer Metabolism
Chapter 20: DNA Replication and Repair
20.1 The DNA Replication Machinery
20.2 Telomeres
20.3 DNA Damage and Repair
20.4 Clinical Connection: Cancer as a Genetic Disease
20.5 DNA Packaging
Chapter 21: Transcription and RNA
21.1 Initiating Transcription
21.2 RNA Polymerase
21.3 RNA Processing
Chapter 22: Protein Synthesis
22.1 tRNA and the Genetic Code
22.2 Ribosome Structure
22.3 Translation
22.4 Post-Translational Events
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