- Introduction
- Basic properties of materials
2.1 Mechanical properties
2.1.1 Tensile testing
2.1.2 Compressive testing
2.1.3 Shear testing
2.1.4 Bend or flexural tests
2.1.5 Viscoelastic behavior
2.1.6 Ductile and brittle fracture
2.1.7 Stress concentration
2.1.8 Fracture toughness
2.1.9 Fatigue
2.2 Electrochemical properties
2.2.1 Corrosion
Passivity
2.2.2 Types of corrosion
Uniform attack
Galvanic corrosion
Crevice corrosion
Pitting corrosion
Intergranular corrosion
Leaching
Erosion corrosion
Fretting corrosion
Stress corrosion
2.3 Surface properties
2.3.1 Contact angle
2.3.2 Hardness
2.4 Summary - Biological systems
3.1 The biological environment
3.2 Genetic regulation and control systems
3.3 The plasma membrane
3.3.1 Membranes are phospholipid layers
3.4 Cytoskeleton and motility
3.5 Cell to cell communication pathways
3.6 Cell junctions
3.6.1 Tight junctions
3.6.2 Gap junctions
3.6.3 Adherens and desmosomes
3.7 Cell signaling pathways
3.7.1 Receptors as signaling sensors
3.7.2 Receptor classes
3.7.3 Second messengers and their activation/deactivation
3.8 Biological testing techniques
3.8.1 Probe and labeling technologies
3.8.2 Examination of gene expression
3.8.3 The plasma membrane
3.8.4 Cytoskeleton and motility
3.8.5 Communication between cells
3.8.6 Mapping intracellular signaling
3.9 Summary - Characterization of biomaterials
4.1 Contact angle
4.2 Infrared spectroscopy
4.2.1 Attenuated total reflection (ATR)
4.2.2 Specular reflectance
4.2.3 Infrared reflection absorption spectroscopy (IRRAS)
4.2.4 Diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS)
4.3 X-ray photoelectron spectroscopy
4.4 Secondary ion mass spectrometry
4.5 Atomic force microscopy
4.6 Scanning electron microscopy
4.7 Transmission electron microscopy
4.8 X-ray diffraction (XRD)
4.9 Chromatography
4.9.1 High performance liquid chromatography (HPLC)
4.9.2 Gel permeation chromatography (GPC)
4.10 Summary - Metals: structure and properties
5.1 Titanium and its alloys
5.1.1 Classification of Ti and its alloys based on crystallographic forms
Alpha alloys
Beta alloys
Alpha-beta alloys
5.1.2 Surface properties
5.1.3 Applications
5.2 Stainless steel
5.2.1 Martensitic stainless steels
5.2.2 Ferritic stainless steels
5.2.3 Austenitic stainless steels
316L stainless steel
5.2.4 Duplex stainless steels
5.2.5 Recent developments in stainless steel alloys
5.3 Cobalt-chromium alloys
5.3.1 ASTM F75
5.3.2 ASTM F799
5.3.3 ASTM F90
5.3.4 ASTM F562
5.4 Nitinol
5.5 Tantalum
5.6 Magnesium
5.7 Summary - Polymers
6.1 Molecular structure of polymers
6.1.1 Molecular weight
6.2 Types of polymerization
6.3 Physical states of polymers
6.3.1 Amorphous phase
6.3.2 Crystalline phase
6.4 Common polymeric biomaterials
6.4.1 Polyethylene
6.4.2 Polymethylmethacrylate (PMMA)
6.4.3 Polylactic acid (PLA) and polyglycolic acid (PGA)
6.4.4 Polycaprolactone (PCL)
6.4.5 Other biodegradable polymers
6.4.6 Polyurethanes
6.4.7 Silicones
6.5 Hydrogels
6.5.1 Synthesis of hydrogels
6.5.2 Properties of hydrogels
6.5.3 Applications
6.6 Nanopolymers
6.7 Summary - Ceramics
7.1 General properties
7.2 Classifications
7.2.1 Classification based on form
7.2.2 Classification based on composition
7.2.3 Classification based on reactivity
7.3 Bioceramics
7.3.1 Silicate glass
7.3.2 Alumina (Al2O3)
7.3.3 Zirconia (ZrO2)
7.3.4 Carbon
7.3.5 Calcium phosphates (CaP)
7.3.6 Hydroxyapatite (HA)
7.3.7 Tricalcium phosphate (TCP)
7.3.8 Calcium sulfate (CaSO4.H2O)
7.3.9 Bioactive glass
7.4 Nanoceramics - Natural biomaterials
8.1 Collagen
8.2 Elastin
8.3 Silk
8.4 Chitosan
8.5 Cellulose
8.6 Alginate
8.7 Hyaluronan
8.8 Chondroitin sulfate
8.9 Coral - Surface modification
9.1 Abrasive blasting
9.2 Plasma glow discharge treatments
9.2.1 Direct current glow discharge
9.2.2 Alternating current glow discharge
9.2.3 Capacitively coupled radiofrequency glow discharge
9.2.4 Inductively coupled radiofrequency glow discharge
9.3 Thermal spraying
9.4 Physical vapor deposition (PVD)
9.4.1 Evaporative deposition
9.4.2 Pulsed laser deposition
9.4.3 Sputter deposition
Direct current (d.c.) sputter deposition
Radiofrequency (RF) sputter deposition
Radiofrequency (RF) magnetron sputter deposition
Ion beam sputter deposition
Ion beam-assisted deposition (IBAD)
Dual ion beam sputter deposition
Ion implantation
9.5 Chemical vapor deposition (CVD)
9.6 Grafting
9.7 Self-assembled monolayer (SAM)
9.7.1 Patterning of self-assembled monolayers
9.8 Layer-by-layer (LbL) assembly
9.8.1 Different layer-by-layer (LbL) assembly techniques - Sterilization of biomedical implants
10.1 Common terminology
10.2 Steam sterilization
10.3 Ethylene oxide sterilization
10.4 Gamma radiation sterilization
10.5 Other sterilization methods
10.5.1 Dry heat sterilization
10.5.2 Formaldehyde and glutaraldehyde treatments
10.5.3 Phenolic and hypochloride solution treatments
10.5.4 Ultraviolet (UV) radiation
10.5.5 Electron beam sterilization
10.6 Recently developed methods
10.6.1 Low temperature gas plasma treatment
10.6.2 Gaseous chlorine dioxide treatment - Cell-biomaterial interactions
11.1 The extracellular environment
11.2 Extracellular matrix mimics
11.3 Cell interactions with non-cellular substrates
11.4 Biocompatibility testing and techniques
11.4.1 Immunostaining techniques for studying cell-ECM interactions
11.4.2 Profiling a cell line for its ECM binding characteristics
11.4.3 Immunoprecipitation and Western blotting - Drug delivery systems
12.1 Diffusion controlled drug delivery systems
12.1.1 Membrane controlled reservoir systems
12.1.2 Monolithic matrix systems
12.2 Water penetration controlled drug delivery systems
12.2.1 Osmotic pressure controlled drug delivery systems
12.2.2 Swelling controlled drug delivery system
12.3 Chemically controlled drug delivery systems
12.3.1 Polymer-drug dispersion systems
12.3.2 Polymer-drug conjugate systems
12.4 Responsive drug delivery systems
12.4.1 Temperature-responsive drug delivery systems
12.4.2 pH-responsive drug delivery systems
12.4.3 Solvent-responsive drug delivery systems
12.4.4 Ultrasound-responsive drug delivery systems
12.4.5 Electrically responsive drug delivery systems
12.4.6 Magnetic-sensitive drug delivery systems
12.5 Particulate systems
12.5.1 Polymeric microparticles
12.5.2 Polymeric micelles
12.5.3 Liposomes - Tissue engineering
13.1 Tissue engineering approaches
13.1.1 Assessment of medical need
13.1.2 Selecting a tissue engineering strategy
13.2 Cells
13.2.1 Stem cells
13.2.2 Biopreservation of cells
13.3 Scaffold properties
13.4 Fabrication techniques for polymeric scaffolds
13.4.1 Solvent casting and particulate leaching
13.4.2 Electrospinning
13.4.3 Solid free form fabrication (SFFF)
13.5 Fabrication of natural polymer scaffolds
13.6 Fabrication techniques for ceramic scaffolds
13.6.1 Template sponge coating
13.6.2 Non-sintering techniques
13.7 Assessment of scaffold architecture
13.8 Cell seeded scaffolds
13.8.1 Cell culture bioreactors
13.8.2 Cell seeding
13.8.3 Growth factors
13.8.4 Mechanical modulation
13.9 Assessment of cell and tissue properties
13.9.1 Cellular properties
Morphology
Cell numbers and proliferation
Cell differentiation
13.9.2 Tissue properties
Immunostaining
Mechanical testing
13.10 Challenges in tissue engineering - Clinical applications
14.1 Cardiovascular assist devices
14.2 Cardiovascular stents
14.3 Dental restoration
14.4 Dental implants
14.5 Neural prostheses
14.6 Opthalmology
14.7 Orthopedic implants
14.8 Renal
14.9 Skin application
Sale!
Introduction to Biomaterials Basic Theory With Engineering Applications 1st edition by Ong, Mark Appleford, Gopinath Mani 9781107595378 1107595371
Original price was: $50.00.$35.00Current price is: $35.00.
Authors:J. L. Ong; Mark R. Appleford; Gopinath Mani , Series:Biomedical [27] , Tags:Science; Life Sciences; Biochemistry; Biology; Cell Biology; Molecular Biology; Technology & Engineering; Engineering (General); Mechanical; Materials Science; General; Biomedical , Author sort:Ong, J. L. & Appleford, Mark R. & Mani, Gopinath , Ids:9780521116909 , Languages:Languages:eng , Published:Published:Dec 2014 , Publisher:CAMBRIDGE UNIVERSITY PRESS , Comments:Comments:This succinct textbook gives students the perfect introduction to the world of biomaterials, linking the fundamental properties of metals, polymers, ceramics and natural biomaterials to the unique advantages and limitations surrounding their biomedical applications. Clinical concerns such as sterilization, surface modification, cell-biomaterial interactions, drug delivery systems and tissue engineering are discussed in detail, giving students practical insight into the real-world challenges associated with biomaterials engineering; key definitions, equations and concepts are concisely summarised alongside the text, allowing students to quickly and easily identify the most important information; and bringing together elements from across the book, the final chapter discusses modern commercial implants, challenging students to consider future industrial possibilities. Concise enough to be taught in a single semester, and requiring only a basic understanding of biology, this balanced and accessible textbook is the ideal introduction to biomaterials for students of engineering and materials science.
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ISBN 10: 1107595371
ISBN 13: 9781107595378
Author: J. L. Ong; Mark R. Appleford; Gopinath Mani
This succinct textbook gives students the perfect introduction to the world of biomaterials, linking the fundamental properties of metals, polymers, ceramics and natural biomaterials to the unique advantages and limitations surrounding their biomedical applications. Clinical concerns such as sterilization, surface modification, cell-biomaterial interactions, drug delivery systems and tissue engineering are discussed in detail, giving students practical insight into the real-world challenges associated with biomaterials engineering; key definitions, equations and concepts are concisely summarised alongside the text, allowing students to quickly and easily identify the most important information; and bringing together elements from across the book, the final chapter discusses modern commercial implants, challenging students to consider future industrial possibilities. Concise enough to be taught in a single semester, and requiring only a basic understanding of biology, this balanced and accessible textbook is the ideal introduction to biomaterials for students of engineering and materials science.
Introduction to Biomaterials Basic Theory With Engineering Applications 1st Table of contents:
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