Hormones 2nd Edition by Anthony Norman, Gerald Litwack ISBN 9780125214414 0125214413

Chapter 1: General Considerations of Hormones

I OVERVIEW OF HORMONES, RECEPTORS, AND ENDOCRINOLOGY

II BIOSYNTHESIS OF HORMONES

III HORMONE RECEPTORS

IV MECHANISM OF HORMONAL ACTION

V SUMMARY

Chapter 2: Steroid Hormones: Chemistry, Biosynthesis, and Metabolism

I INTRODUCTION

II CHEMISTRY OF STEROIDS

III BIOSYNTHESIS OF CHOLESTEROL

IV BIOSYNTHESIS OF STEROIDS

V PROPERTIES OF ENZYMES INVOLVED IN STEROID METABOLISM

VI PLASMA TRANSPORT, CATABOLISM, AND EXCRETION OF STEROID HORMONES

Chapter 3: Hypothalamic Releasing Hormones

I INTRODUCTION

II ANATOMICAL, MORPHOLOGICAL, AND PHYSIOLOGICAL RELATIONSHIPS

III CHEMISTRY

IV BIOCHEMISTRY

V CLINICAL ASPECTS

Chapter 4: Posterior Pituitary Hormones

I INTRODUCTION

II ANATOMY AND DEVELOPMENT OF THE POSTERIOR PITUITARY

III CHEMISTRY

IV BIOCHEMISTRY

V BIOLOGICAL AND MOLECULAR ACTIONS

I Mechanism of Action of OT

VI CLINICAL ASPECTS

Chapter 5: Anterior Pituitary Hormones

I INTRODUCTION

II ANATOMICAL, MORPHOLOGICAL, AND PHYSIOLOGICAL RELATIONSHIPS

III CHEMISTRY

IV BIOCHEMISTRY

V PROLACTIN

VI GROWTH HORMONE

VII β-LIPOTROPIN

VIII THYROTROPIC HORMONE

IX ACTH

X GONADOTROPIC HORMONES LH AND FSH

XI ACTH RECEPTOR

XII CLINICAL ASPECTS

Chapter 6: Thyroid Hormones

I INTRODUCTION

II ANATOMICAL AND MORPHOLOGICAL RELATIONSHIPS

III CHEMISTRY

IV BIOCHEMISTRY

V BIOLOGICAL AND MOLECULAR ACTIONS

VI CLINICAL ASPECTS

Chapter 7: Pancreatic Hormones: Insulin and Glucagon

I INTRODUCTION

II ANATOMICAL, MORPHOLOGICAL, AND PHYSIOLOGICAL RELATIONSHIPS

III CHEMISTRY

IV BIOCHEMISTRY

V BIOLOGICAL AND MOLECULAR ACTIONS

VI CLINICAL ASPECTS

Chapter 8: Gastrointestinal Hormones

I INTRODUCTION

II ANATOMICAL, MORPHOLOGICAL, AND PHYSIOLOGICAL RELATIONSHIPS

III CHEMISTRY AND BIOCHEMISTRY

IV BIOLOGICAL AND MOLECULAR ACTIONS

V CLINICAL ASPECTS

Chapter 9: Calcium-Regulating Hormones: Vitamin D, Parathyroid Hormone, Calcitonin

I INTRODUCTION

II ANATOMICAL, MORPHOLOGICAL, AND PHYSIOLOGICAL RELATIONSHIPS

III CHEMISTRY AND BIOCHEMISTRY

IV BIOLOGY AND PHYSIOLOGICAL SIGNIFICANCE

V CLINICAL ASPECTS

Chapter 10: Adrenal Corticoid

I INTRODUCTION

II ANATOMY, DEVELOPMENT, AND CELLULAR FINE STRUCTURE OF THE ADRENAL CORTEX

III CHEMISTRY AND BIOCHEMISTRY

IV BIOLOGICAL AND MOLECULAR ACTIONS

V GLUCOCORTICOID RECEPTOR

VI ZONA RETICULARIS AND DEHYDROEPIANDROSTERONE

VII MINERALOCORTICOID HORMONE

VIII CLINICAL ASPECTS

Chapter 11: Hormones of the Adrenal Medulla

I INTRODUCTION

II ANATOMICAL, MORPHOLOGICAL, AND PHYSIOLOGICAL RELATIONSHIPS

III CHEMISTRY

IV HORMONE ACTION AND BIOCHEMISTRY

V ACTIONS OF EPINEPHRINE

VI ENKEPHALINS

VII CLINICAL ASPECTS

Chapter 12: Androgens

I INTRODUCTION

II ANATOMICAL AND MORPHOLOGICAL RELATIONSHIPS OF THE MALE REPRODUCTIVE SYSTEM

III CHEMISTRY, BIOCHEMISTRY, AND BIOLOGICAL RESPONSES

IV PHYSIOLOGICAL RELATIONSHIPS

V MOLECULAR ACTIONS

VI CLINICAL ASPECTS

Chapter 13: Estrogens and Progestins

I INTRODUCTION

II ANATOMICAL AND MORPHOLOGICAL RELATIONSHIPS OF THE FEMALE REPRODUCTIVE SYSTEM

III CHEMISTRY, BIOCHEMISTRY, AND BIOLOGICAL RESPONSES

IV PHYSIOLOGICAL RELATIONSHIPS

V BIOLOGICAL AND MOLECULAR ACTIONS

VI CLINICAL ASPECTS

Chapter 14: Hormones of Pregnancy and Lactation

I INTRODUCTION

II ANATOMICAL AND MORPHOLOGICAL RELATIONSHIPS

III CHEMISTRY, BIOCHEMISTRY, AND BIOLOGICAL RESPONSES

IV CELL BIOLOGY AND MOLECULAR ACTIONS

V CLINICAL ASPECTS

Chapter 15: Hormones Related to the Kidney and Cardiovascular System

I INTRODUCTION

II ANATOMICAL, MORPHOLOGICAL, AND PHYSIOLOGICAL RELATIONSHIPS

III HOMEOSTASIS OF FLUID, ELECTROLYTES, AND BLOOD PRESSURE

I Prostaglandins

IV Hormones and Blood Cell Production

V HORMONES AND INFLAMMATIO

VI CLINICAL ASPECTS

Chapter 16: Prostaglandins

I INTRODUCTION

II CHEMISTRY

III BIOCHEMISTRY

IV BIOLOGICAL ACTIONS

V LEUKOTRIENES (LTs)

VI CLINICAL ASPECTS

Chapter 17: Thymus Hormones

I INTRODUCTION

II ANATOMICAL AND MORPHOLOGICAL RELATIONSHIPS

III CELL BIOLOGY

IV CHEMISTRY AND BIOCHEMISTRY

V BIOLOGICAL AND MOLECULAR ACTIONS

VI CLINICAL ASPECTS

Chapter 18: Pineal Hormones

I INTRODUCTION

II DEVELOPMENT

III ANATOMY AND CELL BIOLOGY

IV CHEMISTRY

V BIOCHEMISTRY

VI BIOLOGICAL AND MOLECULAR ACTIONS

VII CLINICAL ASPECTS

Chapter 19: Cell Growth Factors

I GROWTH FACTOR SIGNAL TRANSDUCTION

II GROWTH HORMONE (GH) AND SOMATOMEDINS (IGFs)

III INTERACTION OF IGFs WITH RECEPTORS

IV SIGNAL TRANSDUCTION OF RECEPTORS FOR GH, IGFs, AND INSULIN

V EPIDERMAL GROWTH FACTOR (EGF) FAMILY

VI TRANSFORMING GROWTH FACTOR-β(TGF-β) FAMILY

VII PLATELET-DERIVED GROWTH FACTOR (PDGF)

VIII FIBROBLAST GROWTH FACTOR (FGF)

IX NERVE GROWTH FACTOR (NGF)

X HEPATOCYTE GROWTH FACTOR (HGF, SCATTER FACTOR)

Chapter 20: Hormones and Cancer

I INTRODUCTION

II RELATION OF SOME HORMONES TO CARCINOGENS AND DEVELOPMENT OF CANCER FROM INAPPROPRIATE HORMONAL TREATMENT

III HORMONE-RELATED TREATMENT OF CANCER

IV HORMONE RECEPTOR STATUS OF BREAST CANCERS

V ECTOPIC PRODUCTION OF HORMONES BY TUMOR CELLS

VI ONCOGENES AND HORMONAL FUNCTIONS

VII CONCLUSION

Appendix A: Compilation of Most Known Hormones in Higher Mammals and Humans

Appendix B: Human Blood Concentrations of Major Hormones

Appendix C: Clinically Relevant Endocrine Disorders

Appendix D: The Genetic Code

Appendix E: Amino Acid Abbreviations

Appendix F: Units of Measurement in Biological Systems

Index