Transplant Immunology 1st edition by Xian Li, Anthony Jevnikar ISBN 0470658215 9780470658215

Transplant Immunology 1st edition by Xian Li, Anthony Jevnikar – Ebook PDF Instant Download/Delivery. 0470658215  9780470658215
Full download Transplant Immunology 1st edition after payment

Product details:

ISBN 10: 0470658215 
ISBN 13: 9780470658215
Author:  Xian Li, Anthony Jevnikar

With all the complex issues of acceptance or rejection of a transplanted organ, immunology is a key subject for all transplantation clinicians. During recent years, there has been an explosion of research and knowledge in this area.

Produced in association with the American Society of Transplantation, and written by experts within the field, Transplant Immunology provides a comprehensive overview of the topic in relation to clinical transplantation.

Starting with the basic functionality of the immune system, it then moves on to cover the very latest developments in immunosuppressive drugs and protocols, as well as a look at all emerging technologies in the field.

Transplant Immunology 1st Table of contents:

Section 1: Introduction to Transplant Immunology

1. Overview of Transplantation

   • History of organ transplantation
   • Types of organ transplants (e.g., kidney, liver, heart, bone marrow)
   • Basic principles of transplantation

2. The Immune System in Transplantation

   • Components of the immune system (e.g., T-cells, B-cells, antigen-presenting cells)
   • The role of the immune system in recognizing and rejecting foreign tissue
   • Mechanisms of immune tolerance

Section 2: Immune Responses in Transplantation

3. Allorecognition

   • The concept of alloantigens and the role of histocompatibility antigens (MHC)
   • Direct and indirect pathways of alloantigen presentation
   • The immune response to grafts

4. T-cell Mediated Immune Responses

   • Activation of T-cells and T-cell subsets involved in rejection
   • The role of helper T-cells and cytotoxic T-cells in graft rejection
   • Mechanisms of graft destruction (e.g., cytotoxicity, cytokine release)

5. Antibody-Mediated Rejection

   • The role of antibodies in transplant rejection
   • Acute and chronic antibody-mediated rejection
   • Detection and management of donor-specific antibodies

Section 3: Immunosuppressive Therapy

6. Immunosuppressive Drugs

   • Overview of immunosuppressive drugs (e.g., calcineurin inhibitors, corticosteroids, mTOR inhibitors)
   • Mechanisms of action of immunosuppressive agents
   • Side effects and management of immunosuppressive therapy

7. Induction and Maintenance Immunosuppression

   • Strategies for induction therapy (e.g., antibody-based therapy)
   • Long-term immunosuppression protocols and patient management

Section 4: Complications and Challenges in Transplant Immunology

8. Acute and Chronic Rejection

   • The clinical presentation of acute and chronic rejection
   • Histological features of rejection
   • Mechanisms involved in the progression of chronic rejection

9. Infections in Transplant Recipients

   • Risk of infections in immunosuppressed transplant recipients
   • Common infections after transplantation (e.g., CMV, fungal infections)
   • Prevention and management of infections

10. Post-Transplant Malignancy

    • Increased risk of malignancy due to immunosuppression
    • Common cancers in transplant recipients (e.g., skin cancer, lymphomas)
    • Screening and prevention of malignancy

Section 5: Advances in Transplant Immunology

11. Tolerance Induction

    • Mechanisms of transplant tolerance and strategies for inducing tolerance
    • Current research on tolerance induction in clinical transplantation
    • Role of regulatory T-cells in promoting tolerance

12. Stem Cell and Xenotransplantation

    • Stem cell-based therapies in transplantation
    • Challenges and potential of xenotransplantation (transplantation of organs from other species)

13. Personalized Immunotherapy

    • Advances in molecular diagnostics and personalized medicine
    • Tailoring immunosuppressive therapy based on genetic and immune profiling

Section 6: Clinical Transplantation

14. Solid Organ Transplantation

    • Kidney, liver, heart, and lung transplantation
    • Challenges and immunological considerations specific to each organ
    • Strategies for improving graft survival and function

15. Bone Marrow and Hematopoietic Stem Cell Transplantation

    • Immunological challenges in bone marrow and hematopoietic stem cell transplants
    • Graft-versus-host disease (GVHD) and its management
    • Stem cell donor matching and immune reconstitution

People also search for Transplant Immunology 1st:

renal transplant immunology

kidney transplant immunology

renal transplant immunology ppt

introduction of transplant immunology

liver transplant immunology