Basic Pathology 4th Edition by Sunil R Lakhani, Susan Dilly, Caroline Finlayson ISBN 034095003X 9780340950036

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ISBN 10: 034095003X
ISBN 13: 9780340950036
Author: Sunil R Lakhani, Susan Dilly, Caroline Finlayson 

While being both entertaining and enjoyable, this new edition of is a straightforward introduction to pathology and the mechanisms of disease. It puts pathology into its historical, scientific and clinical context for all medical, dental and nursing students and other health professionals. Basic Pathology has been brought fully up-to-date in this new edition, and once again covers four main themes: What is a Disease, Defence Against Disease, Circulatory Disorders, and Disorders of Cell Growth; highlighting key mechanisms and their interplay in producing symptoms, signs and disease. With new cartoons to illustrate key points and make those study hours pass by with ease, the book also retains the much-praised clinical scenarios, historical anecdotes and key facts boxes.

Basic Pathology 4th Table of contents:

Section I: Introduction to Pathology

1. Introduction to Pathology
   • Definition and Scope of Pathology
   • Basic Mechanisms of Disease
   • Principles of Pathology

Section II: Cell Injury and Adaptation 2. Cell Injury and Death

• Mechanisms of Cell Injury
• Reversible and Irreversible Injury
• Necrosis and Apoptosis

3. Cellular Adaptations
   • Hypertrophy, Hyperplasia, Atrophy, and Metaplasia
   • Pathological Calcification
   • Pigments and Deposits

Section III: Inflammation and Repair 4. Acute Inflammation

• Overview of Acute Inflammation
• Inflammatory Mediators
• Acute Inflammatory Responses

5. Chronic Inflammation

   • Causes and Mechanisms of Chronic Inflammation
   • Granulomatous Inflammation

6. Tissue Repair and Regeneration

   • Wound Healing
   • Fibrosis and Scarring
   • Factors Affecting Tissue Repair

Section IV: Hemodynamics 7. Hemostasis and Thrombosis

• Mechanisms of Hemostasis
• Disorders of Hemostasis
• Thrombosis and Embolism

8. Edema and Fluid Balance

   • Mechanisms of Edema Formation
   • Disorders of Fluid Balance

9. Shock

   • Pathophysiology of Shock
   • Types of Shock and Management

Section V: Neoplasia 10. Neoplasia – Definition and Classification of Tumors – Benign and Malignant Tumors – Molecular Basis of Cancer – Tumor Grading and Staging

11. Tumor Invasion and Metastasis
    • Mechanisms of Tumor Invasion
    • Metastasis and Mechanisms of Spread

Section VI: Infectious Diseases 12. Infectious Diseases – Overview of Infectious Agents – Host-Pathogen Interactions – Infections by Bacteria, Viruses, Fungi, and Parasites

Section VII: Immune System Disorders 13. Immune System and Its Disorders – Overview of the Immune System – Hypersensitivity Reactions – Autoimmune Diseases – Immunodeficiency Syndromes

Section VIII: Genetic and Environmental Diseases 14. Genetic Disorders – Inherited Diseases and Genetic Mechanisms – Chromosomal Abnormalities – Single-Gene Defects

15. Environmental and Nutritional Pathology
    • Environmental Diseases (e.g., toxins, pollutants)
    • Nutritional Deficiencies and Excesses

Section IX: Systemic Pathology 16. Cardiovascular Pathology – Atherosclerosis – Ischemic Heart Disease – Heart Failure and Cardiomyopathies – Valvular Heart Disease

17. Respiratory Pathology

    • Pneumonia and Tuberculosis
    • Chronic Obstructive Pulmonary Disease (COPD)
    • Asthma and Pulmonary Embolism

18. Gastrointestinal Pathology

    • Disorders of the Esophagus, Stomach, and Small Intestine
    • Inflammatory Bowel Disease
    • Liver Diseases and Cirrhosis

19. Renal Pathology

    • Glomerular Diseases
    • Acute Kidney Injury and Chronic Kidney Disease
    • Renal Tubular Disorders

20. Endocrine Pathology

    • Disorders of the Thyroid, Adrenal, and Pituitary Glands
    • Diabetes Mellitus
    • Obesity and Metabolic Syndrome

21. Hematopathology

    • Hematological Disorders (e.g., Anemia, Leukemia)
    • Lymphomas and Myelomas
    • Coagulation Disorders

22. Musculoskeletal Pathology

    • Bone and Joint Disorders
    • Muscular Dystrophies and Soft Tissue Tumors

23. Nervous System Pathology

    • Central Nervous System Disorders
    • Brain and Spinal Cord Diseases
    • Neurodegenerative Disorders

24. Reproductive System Pathology

    • Disorders of the Female and Male Reproductive Systems
    • Ovarian and Uterine Pathologies
    • Prostate and Testicular Disorders

25. Skin Pathology

    • Inflammatory Skin Diseases
    • Skin Neoplasms
    • Dermatological Infections

Section X: Pediatric and Geriatric Pathology 26. Pediatric Pathology – Congenital Disorders – Pediatric Tumors and Infections

27. Geriatric Pathology
    • Aging and Age-Related Diseases
    • Pathology of Aging Organ Systems

Section XI: Diagnostic Pathology 28. Laboratory Diagnosis and Techniques – Microscopy and Histology – Cytology and Immunohistochemistry – Molecular Pathology

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